USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q9NS28 USC-OGP 2-DE database:  Q9NS28 Q9NS28 General information about the entry View entry in simple text format Entry name RGS18_HUMAN Primary accession number Q9NS28 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Regulator of G-protein signaling 18; Short=RGS18;. Gene name Name=RGS18 Synonyms=RGS13 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0495: pI=6.37; Mw=29262 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0998: pI=6.36; Mw=27711 SPOT OGP-0999: pI=6.94; Mw=27711 Cross-references UniProtKB/Swiss-Prot Q9NS28; RGS18_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name RGS18_HUMAN Primary accession number Q9NS28 Secondary accession number(s) B2RD23 Sequence was last modified on  October 1, 2000 (version 1) Annotations were last modified on  March 15, 2017 (version 128) Name and origin of the protein Description RecName: Full=Regulator of G-protein signaling 18; Short=RGS18; Gene name Name=RGS18 Synonyms=RGS13 Encoded on Name=RGS18; Synonyms=RGS13 Keywords 3D-structure; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Signal transduction inhibitor. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF076642; AAF80227.1; -; mRNA EMBL AF268036; AAK58589.1; -; mRNA EMBL AL596342; CAH71160.1; -; Genomic_DNA EMBL AL513175; CAH71160.1; JOINED; Genomic_DNA EMBL AK315377; BAG37770.1; -; mRNA EMBL AL513175; CAH70529.1; -; Genomic_DNA EMBL AL596342; CAH70529.1; JOINED; Genomic_DNA EMBL CH471067; EAW91223.1; -; Genomic_DNA EMBL BC020632; AAH20632.1; -; mRNA CCDS CCDS1374.1; -; . RefSeq NP_570138.1; NM_130782.2; . UniGene Hs.440890; -; . PDB 2DLV; NMR; -; A=76-202 PDB 2JM5; NMR; -; A=75-223 PDB 2OWI; NMR; -; A=75-223 PDBsum 2DLV; -; . PDBsum 2JM5; -; . PDBsum 2OWI; -; . ProteinModelPortal Q9NS28; -; . SMR Q9NS28; -; . BioGrid 122160; 5; . DIP DIP-59096N; -; . STRING 9606.ENSP00000356430; -; . iPTMnet Q9NS28; -; . PhosphoSitePlus Q9NS28; -; . BioMuta RGS18; -; . DMDM 15214228; -; . OGP Q9NS28; -; . EPD Q9NS28; -; . PaxDb Q9NS28; -; . PeptideAtlas Q9NS28; -; . PRIDE Q9NS28; -; . DNASU 64407; -; . Ensembl ENST00000367460; ENSP00000356430; ENSG00000150681; . GeneID 64407; -; . KEGG hsa:64407; -; . UCSC uc001gsg.4; human; . CTD 64407; -; . DisGeNET 64407; -; . GeneCards RGS18; -; . HGNC HGNC:14261; RGS18; . HPA HPA028727; -; . HPA HPA045780; -; . MIM 607192; gene; . neXtProt NX_Q9NS28; -; . OpenTargets ENSG00000150681; -; . PharmGKB PA34369; -; . eggNOG KOG3589; Eukaryota; . eggNOG ENOG410YMJD; LUCA; . GeneTree ENSGT00760000118903; -; . HOGENOM HOG000233512; -; . HOVERGEN HBG013233; -; . InParanoid Q9NS28; -; . KO K16449; -; . OMA RVYQLME; -; . OrthoDB EOG091G0BDG; -; . PhylomeDB Q9NS28; -; . TreeFam TF315837; -; . Reactome R-HSA-416476; G alpha (q) signalling events; . Reactome R-HSA-418594; G alpha (i) signalling events; . EvolutionaryTrace Q9NS28; -; . GeneWiki RGS18; -; . GenomeRNAi 64407; -; . PRO PR:Q9NS28; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000150681; -; . CleanEx HS_RGS13; -; . CleanEx HS_RGS18; -; . Genevisible Q9NS28; HS; . GO GO:0005737; C:cytoplasm; IBA:GO_Central; . GO GO:0005886; C:plasma membrane; IBA:GO_Central; . GO GO:0005096; F:GTPase activator activity; IBA:GO_Central; . GO GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl; . GO GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW; . GO GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl; . Gene3D 1.10.196.10; -; 2; . InterPro IPR016137; RGS; . InterPro IPR024066; RGS_subdom1; . Pfam PF00615; RGS; 1; . PRINTS PR01301; RGSPROTEIN; . SMART SM00315; RGS; 1; . SUPFAM SSF48097; SSF48097; 1; . PROSITE PS50132; RGS; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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